Susceptibility to amphotericin B of Candida spp. strains isolated in Ceará, Northeastern Brazil.

نویسندگان

  • Cecília Rocha da Silva
  • Hemerson Iury Ferreira Magalhães
  • Manoel Odorico de Moraes
  • Hélio Vitoriano Nobre Júnior
چکیده

INTRODUCTION Amphotericin B (AMB) is an antifungal agent used extensively in clinical medicine, yet resistance remains low. This study aims to evaluate the susceptibility of Candida spp. against AMB. METHODS For broth microdilution susceptibility testing, 77 strains of Candida spp. were selected (32 C. albicans, 33 C. tropicalis, and 12 C. parapsilosis). The strains were considered susceptible when they exhibited MIC≤1.0µg/ml. RESULTS None of the strains showed an MIC greater than 0.25µg/ml. CONCLUSIONS Further works are necessary, with a higher number of strains, to assess the validity of the results used in this study.

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عنوان ژورنال:
  • Revista da Sociedade Brasileira de Medicina Tropical

دوره 46 2  شماره 

صفحات  -

تاریخ انتشار 2013